Glopedia

Acetyl-L-carnitine

amino acid and derivative - Acetyl-form of L-carnitine. It participates in the transport of fatty acids to the mitochondria for their conversion into energy and easily crosses the blood-brain barrier. ▸ Protocols: Metabolic Activation

Alpha-lipoic acid

cellular compound and antioxidant - An antioxidant that is both water-soluble and fat-soluble, capable of regenerating other antioxidants. It also plays a role in energy metabolism. ▸ Protocols: Brain Focus

Adaptogen

longevity concept - A substance, most often plant-based, that helps the body adapt better to stress and regain its balance. Ginseng, rhodiola, and ashwagandha are examples.

AMPK

longevity concept - An enzyme that acts as a cellular energy sensor. Activated when reserves decrease, it stimulates energy production and promotes cell renewal.

Antioxidant

longevity concept - A molecule that neutralizes free radicals and thus limits the damage caused to cells by oxidation.

Apoptosis

longevity concept - Programmed cell death, a natural process by which the body eliminates damaged or unnecessary cells to maintain tissue balance.

Ashwagandha (Withania somnifera)

plant and plant extract - A flagship plant in Ayurveda, classified among adaptogens. Studied for its role in cortisol regulation and stress resistance. ▸ Protocols: Stress Balance

Astragalus (Astragalus membranaceus)

plant and plant extract - An adaptogenic plant from Chinese pharmacopoeia, studied for its role in cellular defense and immune support. ▸ Protocols: Longevity Core

ATP (adenosine triphosphate)

longevity concept - A molecule that serves as the energy currency of the cell. Produced mainly in the mitochondria, it fuels almost all bodily reactions.

Autophagy

longevity concept - A cellular internal recycling mechanism that degrades and reuses damaged components. Often described as a cellular spring cleaning, it is stimulated by fasting and exercise.

Bacopa monnieri

plant and plant extract - An Ayurvedic adaptogenic plant standardized for bacosides, traditionally used to support memory and cognitive functions. ▸ Protocols: Brain Focus

Bergamot (Citrus bergamia)

plant and plant extract - Fruit extract, rich in polyphenols and flavonoids, studied for its role in lipid metabolism and cardiometabolic comfort. ▸ Protocols: Metabolic Activation

Beta-carotene

cellular compound and antioxidant - An antioxidant plant pigment that the body converts into vitamin A as needed. It helps protect cells and maintain normal skin. ▸ Protocols: Antioxydative Balance

Bioavailability

longevity concept - The proportion of a nutrient actually absorbed and utilized by the body after ingestion. A highly bioavailable form acts at a lower dose.

Magnesium bisglycinate

mineral and trace element - Magnesium bound to two glycine molecules, a chelated form known for its good absorption and digestive gentleness. Magnesium is involved in over 300 enzymatic reactions, supports the nervous system, and helps reduce fatigue. ▸ Protocols: NAD+ Support · Longevity Core · Brain Focus · Stress Balance

Zinc bisglycinate

mineral and trace element - Chelated form of zinc bound to glycine, appreciated for its high bioavailability and good tolerance. Zinc supports immunity and protects cells from oxidative stress. ▸ Protocols: NAD+ Support · Longevity Core

Green coffee (chlorogenic acid)

plant and plant extract - Extract of unroasted coffee beans, standardized for chlorogenic acid, a polyphenol studied for its influence on glucose metabolism and energy expenditure. ▸ Protocols: Metabolic Core

Cinnamon (Cinnamomum)

plant and plant extract - Bark extract rich in polyphenols, studied for its role in glucose metabolism. ▸ Protocols: Metabolic Core

Carotenoid

longevity concept - A yellow, orange, or red plant pigment with antioxidant properties. Lutein and beta-carotene are examples.

Choline citrate

amino acid and derivative - Choline salt, a nutrient precursor to acetylcholine and a component of cell membranes. Citrate improves its solubility and assimilation. ▸ Protocols: Metabolic Activation

Coenzyme Q10

cellular compound and antioxidant - Also known as ubiquinone, a molecule present in mitochondria where it is involved in cellular energy production. It is also a fat-soluble antioxidant whose levels decline with age. ▸ Protocols: Metabolic Core · NAD+ Support · Antioxydative Balance

Cortisol

longevity concept - The main stress hormone, secreted by the adrenal glands. Useful in the short term, its prolonged excess affects sleep, metabolism, and immunity.

Epigenetics

longevity concept - The set of chemical marks that modulate gene expression without modifying the DNA itself. They evolve with age and lifestyle and are among the markers of biological age.

Healthy life expectancy

longevity concept - The number of years lived without major illness or loss of autonomy. This is the central goal of longevity, often referred to as healthspan.

Flavonoid

longevity concept - A family of polyphenols found in fruits, vegetables, and tea, known for their antioxidant activity.

Ginkgo biloba

plant and plant extract - Leaf extract standardized for flavonoids and terpenes, known for its support of microcirculation, especially cerebral. ▸ Protocols: Brain Focus

Konjac glucomannan

plant and plant extract - Soluble fiber derived from the konjac root. In contact with water, it forms a viscous gel that increases the feeling of fullness. ▸ Protocols: Metabolic Regulate

Zinc gluconate

mineral and trace element - A well-tolerated form of zinc, an essential trace element for the functioning of hundreds of enzymes, immunity, and the protection of cells against oxidative stress. ▸ Protocols: Metabolic Core · Antioxydative Balance

Glycation

longevity concept - A reaction during which sugars attach to proteins and alter them. It accelerates tissue aging and is favored by high blood sugar levels.

Blood sugar

longevity concept - The level of glucose in the blood. Its proper regulation is one of the pillars of metabolic health and longevity.

Gymnema sylvestre

plant and plant extract - A climbing plant from Ayurvedic medicine. Its gymnemic acids are traditionally associated with the regulation of sugar appetite and glycemic comfort. ▸ Protocols: Metabolic Regulate

Homeostasis

longevity concept - The body's ability to maintain its internal balance, such as temperature, blood sugar, or pH, despite external variations.

Chronic inflammation

longevity concept - Low-grade inflammation that persists over time. Silent, it contributes to aging and many age-related diseases. It is also known as inflammaging.

Insulin

longevity concept - A hormone that allows glucose to enter cells and regulates blood sugar. Good insulin sensitivity is essential for metabolism.

L-Carnosine

amino acid and derivative - A dipeptide naturally present in muscles and the brain, formed from beta-alanine and histidine. Recognized for its antioxidant properties and its action against protein glycation. ▸ Protocols: Metabolic Core

Selenium yeast

mineral and trace element - Selenium incorporated into yeast, a highly assimilable organic form. Selenium helps protect cells from oxidative stress. ▸ Protocols: Antioxydative Balance

Longevity

longevity concept - The lifespan of an individual. In health, the term mainly refers to extending the years lived in good health, distinct from mere life expectancy.

Metabolism

longevity concept - The set of chemical reactions that convert what we eat into energy and materials for cells.

Microbiota

longevity concept - A community of microorganisms, especially intestinal, that participates in digestion, immunity, and the body's overall balance.

Mitochondrion

longevity concept - A compartment present in almost all cells, nicknamed the power plant because it is where ATP is produced. Its good health is central to aging.

Mitophagy

longevity concept - A targeted form of autophagy that eliminates worn-out mitochondria to make way for new and efficient mitochondria.

mTOR

longevity concept - A signaling pathway that regulates cell growth based on available nutrients. Moderate activity is associated with longevity.

NAD+

cellular compound and antioxidant - Nicotinamide adenine dinucleotide, a coenzyme present in every cell, central to energy production and the activity of sirtuins, the enzymes associated with longevity. Its levels decrease with age. ▸ Protocols: NAD+ Support

Neurotransmitter

longevity concept - A chemical messenger that transmits information between neurons. Dopamine, serotonin, and acetylcholine are examples.

Trace element

longevity concept - A mineral present in very small quantities in the body but essential for its functioning, such as zinc, selenium, or chromium.

Grape seeds (extract, OPC)

plant and plant extract - Rich in oligomeric proanthocyanidins (OPCs), polyphenols among the most powerful antioxidants, which support vascular and cellular protection. ▸ Protocols: Antioxydative Balance

Phosphatidylserine

cellular compound and antioxidant - A phospholipid constituting nerve cell membranes, studied for its role in memory, concentration, and stress response. ▸ Protocols: Brain Focus

Chromium picolinate

mineral and trace element - A highly bioavailable form of chromium, a trace element that helps maintain normal blood sugar levels and the metabolism of macronutrients. ▸ Protocols: Metabolic Activation · Metabolic Regulate · Metabolic Core

Polyphenol

longevity concept - A vast family of antioxidant plant compounds, found notably in grapes, green tea, and berries, studied for their benefits on longevity.

Free radicals

longevity concept - Unstable molecules produced notably by metabolism, which can damage cells. Their excess generates oxidative stress.

Resveratrol

cellular compound and antioxidant - A polyphenol present in grape skin and knotweed (Polygonum). A sirtuin activator, it is studied for its antioxidant effects and its role in cellular longevity. ▸ Protocols: Longevity Core

Selenomethionine

mineral and trace element - An organic form of selenium, essential for protecting cells against oxidative stress and for the proper functioning of the thyroid and immunity. ▸ Protocols: Longevity Core

Cellular senescence

longevity concept - A state in which a cell stops dividing without dying. The accumulation of these senescent cells with age maintains tissue inflammation.

Senolytic

longevity concept - A compound capable of selectively eliminating senescent cells, a highly studied avenue for slowing down aging.

Sirtuins

longevity concept - A family of enzymes involved in cellular repair and longevity, whose activity depends on NAD+.

Magnesium stearate

excipient - A technological agent used in very small quantities to ensure the homogeneity and good flow of the powder during encapsulation. ▸ Protocols: Transversal use

Oxidative stress

longevity concept - An imbalance between free radicals and the body's antioxidant defenses, which leads to cellular damage and contributes to aging.

Marigold (lutein)

plant and plant extract - A flower, natural source of lutein, a carotenoid that accumulates in the retina and helps protect the eyes from light. ▸ Protocols: Antioxydative Balance

Telomere

longevity concept - Protective ends of chromosomes, which shorten with each cell division. Their length is one of the markers of aging.

Green tea (polyphenols)

plant and plant extract - Camellia sinensis extract standardized for polyphenols, notably catechins like EGCG, recognized for their antioxidant activity. ▸ Protocols: Antioxydative Balance

Vitamin B1 (thiamine)

vitamin - A water-soluble vitamin essential for carbohydrate energy metabolism and the proper functioning of the nervous system. ▸ Protocols: Metabolic Core · Brain Focus

Vitamin B6 (P5P)

vitamin - Present here in its active form, pyridoxal-5-phosphate, directly assimilable. It participates in the synthesis of neurotransmitters and helps reduce fatigue. ▸ Protocols: Brain Focus · Stress Balance

Vitamin B9 (folate)

vitamin - A vitamin essential for cell formation, amino acid metabolism, and the functioning of the nervous system. ▸ Protocols: Brain Focus

Vitamin B12 (cobalamin)

vitamin - A vitamin essential for red blood cell formation, the nervous system, and energy metabolism. ▸ Protocols: Brain Focus

Vitamin C (ascorbic acid)

vitamin - A water-soluble antioxidant vitamin, essential for collagen synthesis, immune support, and the protection of cells against oxidative stress. ▸ Protocols: Antioxydative Balance

Vitamin D3 (cholecalciferol)

vitamin - The most active form of vitamin D, naturally synthesized by the skin under the effect of sunlight. It contributes to the maintenance of bones, muscles, and immunity. ▸ Protocols: NAD+ Support

Vitamin E (tocopherol)

vitamin - A major fat-soluble antioxidant vitamin that protects cell membranes and lipids from oxidation. ▸ Protocols: Antioxydative Balance